When it involves smoothing out nice strains and wrinkles, two in style names usually come up: Jeuveau and Botox. Botox is the OG within the neuromodulator house, and Jeuveau is the up-and-coming, fashionable newer therapy. But how do these wrinkle-relaxing injectables evaluate? And which one do you have to select?
If you’re in search of a secure, efficient method to refresh your look with out surgical procedure, this text will stroll you thru the important thing variations, similarities, and all the pieces in between on the subject of Jeuveau vs Botox.
What Are Jeuveau and Botox?
Both Jeuveau and Botox are injectable therapies created from botulinum toxin kind A. They are both a part of the neuromodular class of skincare ingredients which might be utilized in aesthetics to assist stop and erase the signs of aging. Neuromodulators are substances that work by briefly stress-free muscle tissue that trigger wrinkles, particularly in areas just like the brow, between the eyebrows (glabellar strains), and across the eyes (crow’s ft).

When neuromodulators cease these muscle tissue from contracting as strongly, the skin seems smoother and younger. They can be utilized after strains and wrinkles kind, or they can be utilized preventatively.
Jeuveau vs Botox: Quick Comparison
| Feature | Jeuveau | Botox |
|---|---|---|
| FDA Approval | 2019 (beauty use solely) | 2002 (beauty + medical use) |
| Main Use | Aesthetic therapy of wrinkles | Aesthetic & medical therapies |
| Onset of Results | ~2–3 days | ~3–4 days |
| Duration of Results | 3–4 months (as much as 6 in excessive doses) | 3–4 months |
| Cost per Unit | ~20–25% lower than Botox | Typically greater |
| Common Side Effects | Mild headache, injection website bruising | Same as Jeuveau |
| Unique Feature | Made completely for magnificence use | Used for each magnificence and medical points |
So, How Are Jeuveau and Botox Alike?
From a scientific perspective, Jeuveau and Botox are practically similar. Both skincare therapies:
- Use botulinum toxin A to cease muscle contractions
- Have the identical dosing for efficient outcomes (20 models for frown strains)
- Are injected into related facial muscle tissue
- Offer momentary wrinkle smoothing
- Last as much as 3 to 4 months for most individuals

In head-to-head scientific research, Jeuveau matched Botox in each security and wrinkle-reducing energy, with 87% of Jeuveau customers and 83% of Botox customers seeing seen enchancment in frown strains by Day 30. Even for crow’s ft (the little strains round your eyes), Jeuveau carried out simply in addition to Botox in a split-face trial, displaying related outcomes.
What Makes Jeuveau Different?
1. Aesthetic-Only Focus
Jeuveau is the primary neurotoxin designed solely for beauty use. It doesn’t have medical approvals like Botox does for migraines or muscle spasms. This singular focus permits its producer to maintain pricing aggressive and advertising tailor-made for magnificence use. In my opinion, it additionally means they had been capable of concentrate on options which might be vital to magnificence lovers, like quicker performing and limiting uncomfortable side effects from long-term utilization.
2. Cost Advantage
Because Jeuveau isn’t a part of a broader medical portfolio, it’s usually 20–25% inexpensive than Botox for a similar therapy. For individuals doing common touch-ups each few months, that provides as much as actual financial savings over time. Or if you're somebody wanting to present it a attempt for the primary time, this presents you a lower-cost entry level to the therapy.
3. Purity Process
Jeuveau is made with a high-purity technique known as “Hi-Pure,” which can cut back inactive proteins within the system. This might doubtlessly decrease the (already low) danger of constructing resistance after repeated use related to another neuromodulators.
What About Results? Are the Differences Between Jeuveau vs. Botox?

Both Jeuveau and Botox ship quick, noticeable outcomes, however some research present Jeuveau might kick in barely quicker. In scientific research, outcomes from Jeuveau had been sometimes seen in 2-3 days in comparison with 3-4 days for Botox. Specifically, one examine evaluating 4 toxins, Jeuveau confirmed one of many quickest onsets of muscle rest results by Day 3. For anybody looking for outcomes earlier than a giant occasion, this could possibly be a small however significant benefit.
How Long Do Results Last?
For most individuals, for each Jeuveau and Botox, the outcomes lasted largely the identical period of time. Both final roughly 3-4 months at normal dosages and as much as 6 months at greater dosages. Ultimately, everybody’s outcomes are very customized, and you may expertise totally different outcomes.
Who If Jeuveau Best For Compared To Botox?
Everyone can profit from each of those therapies, however Jeuveau confirmed greater satisfaction amongst youthful customers (particularly millennials). In trials, 97% of sufferers below 40 noticed seen outcomes, in comparison with 85% in older teams.
This makes Jeuveau a robust selection for individuals of their 20s and 30s who're beginning preventative therapies early to stop the formation of nice strains and wrinkles.

Jeuveau vs Botox: So Which One Should You Choose?
Ultimately, speak along with your skincare supplier about what therapy ought to be your ultimate step earlier than you pursue any therapy. However, listed below are some normal tips you may use a dialog starters and thought provokers on which take advantage of sense for you:
| If You Want… | Choose… |
|---|---|
| A trusted model with medical makes use of | Botox |
| An economical, beauty-focused possibility | Jeuveau |
| Faster onset and excessive satisfaction in youthful customers | Jeuveau |
| To keep on with what’s extensively identified | Botox |
Both therapies are backed by scientific analysis, FDA-approved, and thought of very secure when carried out by educated professionals.
Are There Any Risks?
The dangers are practically the identical for each. The commonest uncomfortable side effects embody:
- Mild headache
- Bruising on the injection website
- Temporary eyelid drooping (uncommon, ~1–2%)
- Mild redness or swelling
These results are sometimes delicate and resolve on their very own. No severe security considerations have been linked to both product when used cosmetically.
So, What is the Final Verdict On Jeuveau vs Botox
When evaluating Jeuveau vs Botox, there’s no one-size-fits-all reply. Both supply dependable, science-backed wrinkle discount. The proper selection comes all the way down to your objectives, your price range, and your supplier’s suggestion.
References
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Cheon, H.I., Jung, N., Won, C.H., Kim, B.J., & Lee, Y.W. (2019). Efficacy and safety of prabotulinumtoxin A and onabotulinumtoxin A for crow’s feet: a phase 3, multicenter, randomized, double-blind, split-face study. Dermatologic Surgery, 45(12), 1610-1619. DOI: 10.1097/DSS.0000000000001920
Rzany, B.J., Ascher, B., Avelar, R.L., et al. (2020). A multicenter, randomized, double-blind, placebo-controlled, single-dose, phase 3, non-inferiority study comparing prabotulinumtoxinA and onabotulinumtoxinA for the treatment of moderate to severe glabellar lines in adult patients. Aesthetic Surgery Journal, 40(4), 413-429. DOI: 10.1093/asj/sjz110
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Avelar, R.L. (2024). Post hoc analysis comparing the safety and efficacy of prabotulinumtoxinA in millennials and nonmillennials with moderate to severe glabellar lines. Dermatologic Surgery, 50(9 Suppl), S42–S47. DOI: 10.1097/DSS.0000000000004249
Lemdani, M.S., Honig, S.E., Habarth-Morales, T.E., et al. (2025). Comparison of botulinum toxin A formulations for glabellar strain treatment in women: a double-blind randomized clinical trial. JAMA Dermatology, 161(7), 723-730. DOI: 10.1001/jamadermatol.2025.1335
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Fagien, S., Avelar, R.L., Cox, S.E., Joseph, J.H., Kaufman-Janette, J., & Marcus, Ok.A. (2024). Safety and duration of effect of 40-unit prabotulinumtoxinA-xvfs for the treatment of moderate to severe glabellar lines in adult patients: a phase II, multicenter, randomized, double-blind, active-controlled trial. Aesthetic Surgery Journal, 44(9), 987-1000. DOI: 10.1093/asj/sjae051
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